I'll use Jordan Zimmermann's 2010-11 experience as our barometer, then offer a poll. I guess this is somewhat of an attempt at what they call "crowdsourcing."
Zimmermann in 2010 threw 70.2 innings total (39.2 in minors, 31 in majors)
In 2011 Zimmermann threw 161.1 innings total.
Expressed in raw numbers, it was a 90.2 innings jump.
Expressed in a percentage, it was a 128.3% jump.
In 2011 Strasburg threw 44.1 innings total (20.1 in minors, 24 in majors)
A 90.2 innings jump would put him at 135 innings for 2012.
A 128.3% jump would put him at 101.1 innings.
Let's also consider Zimmerman's 161.1 innings this season.
You may consider additional possible factors, of course, e.g. contention (please yes!), re-injury (please no...), etc.
The poll is below. Vote and discuss.